You’re More Likely to Get Cancer Living In Iowa—Here’s Why

Iowa has the second-highest cancer rate in the U.S. and the fastest-growing rate of new diagnoses, with an estimated 21,700 new cases in 2026. 

Based on recent research, people in Iowa are about 10% to 15% more likely to be diagnosed with cancer compared to the national average.

The Numbers Behind the Headline

Iowa currently ranks as having the 2nd-highest cancer rate in the United States.

Even more concerning:

• 87 out of 99 counties in Iowa have cancer rates higher than the national average
• Rates in Iowa are still increasing, while many other states are seeing declines

This means the higher risk isn’t isolated—it’s something impacting nearly the entire state.

The Counties Seeing the Highest Rates

While most of Iowa is above average, some counties stand out.

Cass County ranks among the highest in the state for cancer rates. Palo Alto County has also reported rates significantly above the national average.

In eastern Iowa, several counties near the Quad Cities are also elevated, including:

• Clinton County
• Scott County
• Muscatine County
• Jackson County
• Polk County, which includes Des Moines, also reports rates higher than the U.S. average.

The takeaway is simple: this isn’t just one area—it’s happening across both rural and urban communities.

What’s Causing the Increased Risk?

There isn’t one single answer, but one of the biggest factors is something many people don’t think about: radon.

Radon is a radioactive gas that forms naturally in the ground when uranium breaks down in soil and rock.

It’s especially dangerous because it is:

• Invisible
• Odorless
• Tasteless

Radon can seep into homes through cracks in the foundation and build up over time without anyone noticing.

Why this matters:

It is the second leading cause of lung cancer in the U.S. Iowa has some of the highest radon levels in the country. For many residents, exposure is happening daily without them even knowing it.

Other Factors That May Be Contributing

Researchers are also looking at additional possible causes, including:

• Environmental Exposure
• Agricultural chemicals like pesticides and herbicides
• Nitrates in drinking water

While these are still being studied, no single environmental factor has been confirmed as the main cause.

Lifestyle Trends

Iowa ranks relatively high in:

• Alcohol use
• Tobacco use

These are known to increase the risk of several types of cancer, including breast, liver, and throat cancers.

Age and Detection

Iowa has an older population on average, and cancer risk increases with age. More screening and early detection also mean more cases are being diagnosed.

The Bottom Line

Living in Iowa doesn’t mean you WILL get cancer—but statistically, you are more likely to be diagnosed than someone living in many other states.

Experts believe the higher risk comes from a combination of:

• High radon exposure
• Environmental factors
• Lifestyle habits
• Aging population
• Increased detection

What You Can Do

While the statistics can feel overwhelming, there are practical steps you can take:

• Test your home for radon
• Stay up to date on cancer screenings
• Avoid smoking and limit alcohol use
• Protect your skin from sun exposure

Awareness is key—and in a state like Iowa, it matters more than most.